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PONAB CHI3L1 (a.a. 49-410)
Pongo abelii CHI3L1 Swiss Prot#
Q5RBP6
Pongo abelii CHI3L1 Protein names
Chitinase-3-like protein 1
Pongo abelii CHI3L1 Gene names
CHI3L1
Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Pongo abelii CHI3L1 Entry name
CH3L1_PONAB
Pongo abelii CHI3L1 Codon optimized cDNA Clone
Pongo abelii CHI3L1 cDNA Cat#
RPQ-2494-0004
cDNA Tag
cDNA Pongo abelii CHI3L1 contains A 6x histidine tag
Condon optimized Pongo abelii CHI3L1 cDNA Formulation
Liquid
Condon optimized Pongo abelii CHI3L1 cDNA Storage
Ship at Room temperature. Storage at -20°C to -80°C Upon receipt. Avoid repeated freeze-thaw
Condon optimized Pongo abelii CHI3L1 cDNA Applications
Applications:
1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.
2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Pongo abelii CHI3L1 Protein
Recombinant Pongo abelii CHI3L1 Protein Cat#
PQ-2494-0004
Pongo abelii CHI3L1 Protein Source
Recombinant protein
Recombinant Pongo abelii CHI3L1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pongo abelii CHI3L1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pongo abelii CHI3L1 Protein Activity
NA
Recombinant protein Tag
Recombinant Pongo abelii CHI3L1 Contains A 6x histidine tag
Recombinant Pongo abelii CHI3L1 Protein Formulation
Liquid
Recombinant Pongo abelii CHI3L1 Protein Storage
Ship at 4°C. Storage at -20°C to -80°C Upon receipt. Avoid repeated freeze-thaw
Place Order for Recombinant Pongo abelii CHI3L1 Protein or cDNA
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Pongo abelii CHI3L1 Protein family
-
Pongo abelii CHI3L1 Subcellular locations
Secreted extracellular space. Cytoplasm. Cytoplasm perinuclear region. Endoplasmic reticulum.
Pongo abelii CHI3L1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs.

Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also

regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).
Pongo abelii CHI3L1 Sequence databases
DDBJ EMBL GenBank
Pongo abelii CHI3L1 3D structure databases
ModBase
Pongo abelii CHI3L1 Protein protein interaction databases
STRING
Pongo abelii CHI3L1 Proteomic databases
PRIDE
Pongo abelii CHI3L1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Pongo abelii CHI3L1 Organism specific databases
CTD MGI
Pongo abelii CHI3L1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OMA OrthoDB PhylomeDB
Pongo abelii CHI3L1 Gene expression databases
ArrayExpress Bgee Genevestigator
Pongo abelii CHI3L1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY