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Magnetic Beads Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Reversed-Phase Beads  
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Ion Exchange
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Antibody Purification & IP
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Antibody Immobilization
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Recombinant Protein
Purification
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Peptide Immobilization
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Human SMAD7 (aa 1-426)
SMAD7 Swiss Prot#
O15105
SMAD7 Protein names
Mothers against decapentaplegic homolog 7 (Mothers against DPP homolog

7) (SMAD 7) (Smad7) (hSMAD7)
SMAD7 Gene names
SMAD7 (MADH7) (MADH8)
Organism
Homo sapiens (Human)
SMAD7 Entry name
SMAD7_HUMAN
SMAD7 Codon optimized cDNA Clone
SMAD7 cDNA Cat#
RPM0128
cDNA Tag
cDNA SMAD7 Contains A 6x histidine tag
Condon optimized SMAD7 cDNA Formulation
Liquid
Condon optimized SMAD7 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized SMAD7 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant SMAD7 Protein
Recombinant SMAD7 Protein Cat#
PM0128
SMAD7 Protein Source
Recombinant protein.
Recombinant SMAD7 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant SMAD7 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant SMAD7 Protein Activity
N/A
Recombinant protein Tag
Recombinant SMAD7 contains A 6x histidine tag
Recombinant SMAD7 Protein Formulation
Liquid
Recombinant SMAD7 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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SMAD7 Protein family
Dwarfin/SMAD family
SMAD7 Subcellular locations
Nucleus. Cytoplasm.
SMAD7 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Antagonist of signaling by TGF-beta (transforming growth factor)

type 1 receptor superfamily members; has been shown to inhibit TGF-beta

(Transforming growth factor) and activin signaling by associating with their

receptors thus preventing SMAD2 access. Functions as an adapter to

recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting

the PPP1R15A-PP1 complex to TGFBR1, which promotes its

dephosphorylation.
SMAD7 Sequence databases
EMBL DDBJ GenBank
SMAD7 3D structure databases
ModBase
SMAD7 Protein-protein interaction databases
STRING
SMAD7 Proteomic databases
PRIDE
SMAD7 Genome annotation databases
Ensembl GeneID KEGG UCSC
SMAD7 Organism specific databases
CTD MGI
SMAD7 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
SMAD7 Gene expression databases
Bgee ArrayExpress Genevestigator
SMAD7 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY