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Magnetic Beads Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Reversed-Phase Beads  
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Ion Exchange
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Antibody Purification & IP
  • Protein A
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Antibody Immobilization
  • Protein A
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Recombinant Protein
Purification
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Peptide Immobilization
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Carbohydrate
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Abundant Protein Removal
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    or Gene name, or Protein Name, or Accession Number
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Human DKK4 (aa 19-224 )
DKK4 Swiss Prot#
Q9UBT3
DKK4 Protein names
Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4) (hDkk-4) [Cleaved into:

Dickkopf-related protein 4 short form]
DKK4 Gene names
DKK4
Organism
Homo sapiens (Human)
DKK4 Entry name
DKK4_HUMAN
DKK4 Codon optimized cDNA Clone
DKK4 cDNA Cat#
RPM0157
cDNA Tag
cDNA DKK4 Contains A 6x histidine tag
Condon optimized DKK4 cDNA Formulation
Liquid
Condon optimized DKK4 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized DKK4 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant DKK4 Protein

Recombinant DKK4 Protein Cat#
PM0157
DKK4 Protein Source
Recombinant protein.
Recombinant DKK4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DKK4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DKK4 Protein Activity
N/A
Recombinant protein Tag
Recombinant DKK4 contains A 6x histidine tag
Recombinant DKK4 Protein Formulation
Liquid
Recombinant DKK4 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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DKK4 Protein family
Dickkopf family
DKK4 Subcellular locations
Secreted.
DKK4 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Antagonizes canonical Wnt signaling by inhibiting LRP5/6

interaction with Wnt and by forming a ternary complex with the

transmembrane protein KREMEN that promotes internalization of LRP5/6.

DKKs play an important role in vertebrate development, where they locally

inhibit Wnt regulated processes such as antero-posterior axial patterning,

limb development, somitogenesis and eye formation. In the adult, Dkks are

implicated in bone formation and bone disease, cancer and Alzheimer

disease (By similarity).
DKK4 Sequence databases
EMBL DDBJ GenBank
DKK4 3D structure databases
ModBase
DKK4 Protein-protein interaction databases
STRING
DKK4 Proteomic databases
PRIDE
DKK4 Genome annotation databases
Ensembl GeneID KEGG UCSC
DKK4 Organism specific databases
CTD MGI
DKK4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DKK4 Gene expression databases
Bgee ArrayExpress Genevestigator
DKK4 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY