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Magnetic Beads Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Reversed-Phase Beads  
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Ion Exchange
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Antibody Purification & IP
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Antibody Immobilization
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Recombinant Protein
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Human SKP1 (aa 2-163)
SKP1 Swiss Prot#
P63208
SKP1 Protein names
S-phase kinase-associated protein 1 (Cyclin A/CDK2-associated protein

p19) (p19skp1) (p19A) (RNA polymerase II elongation factor-like protein)

(Organ of Corti protein 2) (OCP-2) (OCP-II) (Transcription elongation factor B)

(SIII)
SKP1 Gene names
SKP1 (EMC19) (OCP2) (SKP1A) (TCEB1L)
Organism
Homo sapiens (Human)
SKP1 Entry name
SKP1_HUMAN
SKP1 Codon optimized cDNA Clone
SKP1 cDNA Cat#
RPM0190
cDNA Tag
cDNA SKP1 Contains A 6x histidine tag
Condon optimized SKP1 cDNA Formulation
Liquid
Condon optimized SKP1 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized SKP1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant SKP1 Protein

Recombinant SKP1 Protein Cat#
PM0190
SKP1 Protein Source
Recombinant protein.
Recombinant SKP1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant SKP1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant SKP1 Protein Activity
N/A
Recombinant protein Tag
Recombinant SKP1 contains A 6x histidine tag
Recombinant SKP1 Protein Formulation
Liquid
Recombinant SKP1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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SKP1 Protein family
SKP1 family
SKP1 Subcellular locations
-
SKP1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Essential component of the SCF (SKP1-CUL1-F-box protein)

ubiquitin ligase complex, which mediates the ubiquitination of proteins

involved in cell cycle progression, signal transduction and transcription. In

the SCF complex, serves as an adapter that links the F-box protein to CUL1.

SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22';

the degradation frees the associated NFKB1-RELA dimer to translocate into

the nucleus and to activate transcription. SCF(Cyclin F) directs

ubiquitination of CP110.
SKP1 Sequence databases
EMBL DDBJ GenBank
SKP1 3D structure databases
ModBase
SKP1 Protein-protein interaction databases
STRING
SKP1 Proteomic databases
PRIDE
SKP1 Genome annotation databases
Ensembl GeneID KEGG UCSC
SKP1 Organism specific databases
CTD MGI
SKP1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
SKP1 Gene expression databases
Bgee ArrayExpress Genevestigator
SKP1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY