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Human TANK (aa 1-425)

TANK Swiss Prot#

Q92844

TANK Protein names

TRAF family member-associated NF-kappa-B activator (TRAF-interacting

protein) (I-TRAF)

TANK Gene names

TANK (ITRAF) (TRAF2)

Organism

Homo sapiens (Human)

TANK Entry name

TANK_HUMAN

TANK Codon optimized cDNA Clone

TANK CDNA Cat#

RPM0032

cDNA Tag

cDNA TANK Contains A 6x histidine tag

Condon optimized TANK CDNA Formulation

Liquid

Condon optimized TANK CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TANK cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TANK Protein

Recombinant TANK Protein Cat#

PM0032

TANK Protein Source

Recombinant protein.

Recombinant TANK Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TANK Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TANK Protein Activity

N/A

Recombinant protein Tag

Recombinant TANK contains A 6x histidine tag

Recombinant TANK Protein Formulation

Liquid

Recombinant TANK Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TANK Protein family

TANK Subcellular locations

Cytoplasm.

TANK FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Acts as a regulator of TRAF function by maintaining them in a

latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation

signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and

inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-

B-kinase (IKK) regulation; may function as an adapter for kinases such as

TBK1 or IKBKE that can modulate IKK activity.

TANK Sequence databases

EMBL

DDBJ

GenBank

TANK 3D structure databases

ModBase

TANK Protein-protein interaction databases

STRING

TANK Proteomic databases

PRIDE

TANK Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TANK Organism specific databases

CTD

MGI

TANK Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TANK Gene expression databases

Bgee

ArrayExpress

Genevestigator

TANK Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY