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Magnetic Beads Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Reversed-Phase Beads  
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Ion Exchange
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Antibody Purification & IP
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Antibody Immobilization
  • Protein A
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Recombinant Protein
Purification
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Peptide Immobilization
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Immobilization
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  • For cDNA or Recombinant Protein Search ( Input Cat#,
    or Gene name, or Protein Name, or Accession Number
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Mouse H2afy (aa 2-372)
H2afy Swiss Prot#
Q9QZQ8
H2afy Protein names
Core histone macro-H2A.1 (Histone macroH2A1) (mH2A1) (H2A.y) (H2A/y)
H2afy Gene names
H2afy
Organism
Mus musculus (Mouse)
H2afy Entry name
H2AY_MOUSE
H2afy Codon optimized cDNA Clone
H2afy CDNA Cat#
RPM0361
cDNA Tag
cDNA H2afy Contains A 6x histidine tag
Condon optimized H2afy CDNA Formulation
Liquid
Condon optimized H2afy CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized H2afy cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant H2afy Protein
Recombinant H2afy Protein Cat#
PM0361
H2afy Protein Source
Recombinant protein.
Recombinant H2afy Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant H2afy Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant H2afy Protein Activity
N/A
Recombinant protein Tag
Recombinant H2afy contains A 6x histidine tag
Recombinant H2afy Protein Formulation
Liquid
Recombinant H2afy Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Place Order for Recombinant H2afy Protein or cDNA
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H2afy Protein family
-
H2afy Subcellular locations
Nucleus. Chromosome.
H2afy FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Variant histone H2A which replaces conventional H2A in a

subset of nucleosomes where it represses transcription. Nucleosomes

wrap and compact DNA into chromatin, limiting DNA accessibility to the

cellular machineries which require DNA as a template. Histones thereby

play a central role in transcription regulation, DNA repair, DNA replication

and chromosomal stability. DNA accessibility is regulated via a complex set

of post-translational modifications of histones, also called histone code,

and nucleosome remodeling. Involved in stable X chromosome

inactivation. Inhibits the binding of transcription factors and interferes with

the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation

by EP300 and recruits class I HDACs, which induces an hypoacetylated

state of chromatin. In addition, isoform 1, but not isoform 2, binds ADP-

ribose and O-acetyl-ADP-ribose, and may be involved in ADP-ribose-

mediated chromatin modulation.
H2afy Sequence databases
EMBL DDBJ GenBank
H2afy 3D structure databases
ModBase
H2afy Protein-protein interaction databases
STRING
H2afy Proteomic databases
PRIDE
H2afy Genome annotation databases
Ensembl GeneID KEGG UCSC
H2afy Organism specific databases
CTD MGI
H2afy Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
H2afy Gene expression databases
Bgee ArrayExpress Genevestigator
H2afy Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY