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Mouse Pias4 (aa 1-507)
Pias4 Swiss Prot#
Q9JM05
Pias4 Protein names
E3 SUMO-protein ligase PIAS4 (Protein inhibitor of activated STAT protein 4)

(Protein inhibitor of activated STAT protein gamma) (PIAS-gamma) (PIASy)
Pias4 Gene names
Pias4 (Piasg)
Organism
Mus musculus (Mouse)
Pias4 Entry name
PIAS4_MOUSE
Pias4 Codon optimized cDNA Clone
Pias4 CDNA Cat#
RPM0383
cDNA Tag
cDNA Pias4 Contains A 6x histidine tag
Condon optimized Pias4 CDNA Formulation
Liquid
Condon optimized Pias4 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized Pias4 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Pias4 Protein
Recombinant Pias4 Protein Cat#
PM0383
Pias4 Protein Source
Recombinant protein.
Recombinant Pias4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pias4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pias4 Protein Activity
N/A
Recombinant protein Tag
Recombinant Pias4 contains A 6x histidine tag
Recombinant Pias4 Protein Formulation
Liquid
Recombinant Pias4 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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Pias4 Protein family
PIAS family
Pias4 Subcellular locations
Nucleus > PML body.
Pias4 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Functions as an E3-type small ubiquitin-like modifier (SUMO)

ligase, stabilizing the interaction between UBE2I and the substrate, and as a

SUMO-tethering factor. Plays a crucial role as a transcriptional

coregulation in various cellular pathways, including the STAT pathway, the

p53 pathway, the Wnt pathway and the steroid hormone signaling pathway.

Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling,

represses Lef1 and enhances TCF4 transcriptional activities.
Pias4 Sequence databases
EMBL DDBJ GenBank
Pias4 3D structure databases
ModBase
Pias4 Protein-protein interaction databases
STRING
Pias4 Proteomic databases
PRIDE
Pias4 Genome annotation databases
Ensembl GeneID KEGG UCSC
Pias4 Organism specific databases
CTD MGI
Pias4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Pias4 Gene expression databases
Bgee ArrayExpress Genevestigator
Pias4 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY