Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Interferon regulatory factor 3 Protein
Recombinant Interferon regulatory factor 3 Protein Cat#
PA0120
Interferon regulatory factor 3 Protein Source
Recombinant protein.
Recombinant Interferon regulatory factor 3 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Interferon regulatory factor 3 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Interferon regulatory factor 3 Protein Activity
N/A
Recombinant protein Tag
Recombinant Interferon regulatory factor 3 Contains A 6x histidine tag
Recombinant Interferon regulatory factor 3 Protein Formulation
Liquid
Recombinant Interferon regulatory factor 3 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Interferon regulatory factor 3 Protein or cDNA
Interferon regulatory factor 3 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-
terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates
the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains.
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
