Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Carbohydrate sulfotransferase 4 Protein
Recombinant Carbohydrate sulfotransferase 4 Protein Cat#
PA0019
Carbohydrate sulfotransferase 4 Protein Source
Recombinant protein.
Recombinant Carbohydrate sulfotransferase 4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Carbohydrate sulfotransferase 4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Carbohydrate sulfotransferase 4 Protein Activity
N/A
Recombinant protein Tag
Recombinant Carbohydrate sulfotransferase 4 Contains A 6x histidine tag
Recombinant Carbohydrate sulfotransferase 4 Protein Formulation
Liquid
Recombinant Carbohydrate sulfotransferase 4 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Carbohydrate sulfotransferase 4 Protein or cDNA
Golgi apparatus membrane; Single-pass type II membrane protein.
Carbohydrate sulfotransferase 4 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Catalyzes the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues within mucin-associated glycans that ultimately serve as L-selectin ligands. L-selectin ligands are present in high endothelial
cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Participates in biosynthesis of L-selectin ligand sialyl 6-sulfo Lewis X on L-selectin counter receptors CD43, GlyCAM-1 and MAdCAM-1. Also involved in
biosynthesis of L-selectin ligand recognized by MECA-79 antibody. Plays a central role in lymphocyte trafficking during chronic inflammation. Has a catalytic preference for core 2-branched mucin-type O-glycans. Can use GlcNAcbeta1-6[Galbeta1-
3]GalNAc-pNP (core 2), GlcNAcbeta1-6ManOMe and GlcNAcbeta1-2Man oligosaccharide structures as acceptors. Has also activity toward core 3 of GlcNAcbeta1-3GalNAc-pNP. Its substrate specificity may be influenced by its subcellular location.
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
