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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Mouse Gcg (aa 21-180)
Gcg Swiss Prot#
P55095
Gcg Protein names
Glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP)

Oxyntomodulin (OXY) (OXM) Glucagon; Glucagon-like peptide 1 (GLP-1)

Glucagon-like peptide 1(7-37) (GLP-1(7-37)) Glucagon-like peptide 1(7-36)

(GLP-1(7-36)) Glucagon-like peptide 2 (GL
Gcg Gene names
Gcg
Organism
Mouse
Gcg Entry name
GLUC_MOUSE
Gcg Codon optimized cDNA Clone
Gcg CDNA Cat#
RPU0199
cDNA Tag
cDNA Gcg Contains A 6x histidine tag
Condon optimized Gcg CDNA Formulation
Liquid
Condon optimized Gcg CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized Gcg cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

recombinant Gcg Protein
recombinant Gcg Protein Cat#
PU0199
Gcg Protein Source
recombinant protein.
recombinant Gcg Protein Applications
Western Blot, may be used for other applications determined by user
recombinant Gcg Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
recombinant Gcg Protein Activity
N/A
recombinant protein Tag
recombinant Gcg contains A 6x histidine tag
recombinant Gcg Protein Formulation
Liquid
recombinant Gcg Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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Gcg Protein family
Glucagon family
Gcg Subcellular locations
Secreted.
Gcg FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Glucagon plays a key role in glucose metabolism and

homeostasis. Regulates blood glucose by increasing gluconeogenesis and

decreasing glycolysis. A counterregulatory hormone of insulin, raises

plasma glucose levels in response to insulin-induced hypoglycemia (By

similarity).; FUNCTION: GLP-1 is a potent stimulator of glucose-dependent

insulin release. Play important roles on gastric motility and the suppression

of plasma glucagon levels. May be involved in the suppression of satiety

and stimulation of glucose disposal in peripheral tissues, independent of the

actions of insulin. Have growth-promoting activities on intestinal

epithelium. May also regulate the hypothalamic pituitary axis (HPA) via

effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases

islet mass through stimulation of islet neogenesis and pancreatic beta cell

proliferaton (By similarity).; FUNCTION: GLP-2 stimulates intestinal growth

and up-regulates villus height in the small intestine, concomitant with

increased crypt cell proliferation and decreased enterocyte apoptosis. The

gastrointestinal tract, from the stomach to the colon is the principal target

for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing

nutrient assimilation through enhanced gastrointestinal function, as well as

increasing nutrient disposal. Stimulates intestinal glucose transport and

decreases mucosal permeability (By similarity).; FUNCTION: Oxyntomodulin

significantly reduces food intake (By similarity).; FUNCTION: Glicentin may

modulate gastric acid secretion and gastro-pyloro-duodenal activity.
Gcg Sequence databases
EMBL DDBJ GenBank
Gcg 3D structure databases
ModBase
Gcg Protein-protein interaction databases
STRING
Gcg Proteomic databases
PRIDE
Gcg Genome annotation databases
Ensembl GeneID KEGG UCSC
Gcg Organism specific databases
CTD MGI
Gcg Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Gcg Gene expression databases
Bgee ArrayExpress Genevestigator