Human Pleckstrin homology domain-containing family O 1 (aa 1-409)
Pleckstrin homology domain-containing family O 1 Swiss Prot#
Q53GL0
Pleckstrin homology domain-containing family O 1 Protein names
Pleckstrin homology domain-containing family O member 1 (Casein kinase 2-interacting protein 1) (CK2-interacting protein-1) (CKIP-1) (C-Jun-binding protein) (JBP) (Osteoclast maturation associated gene 120 protein)
Pleckstrin homology domain-containing family O 1 Gene names
PLEKHO1 (CKIP1) (OC120) (HQ0024c)
Organism
Human
Pleckstrin homology domain-containing family O 1 Entry name
PKHO1_HUMAN
Pleckstrin homology domain-containing family O 1 Codon optimized cDNA Clone
Pleckstrin homology domain-containing family O 1 CDNA Cat#
RPA0200
cDNA Tag
cDNA Pleckstrin homology domain-containing family O 1 Contains A 6x histidine tag
Condon optimized Pleckstrin homology domain-containing family O 1 CDNA Formulation
Liquid
Condon optimized Pleckstrin homology domain-containing family O 1 cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Pleckstrin homology domain-containing family O 1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Pleckstrin homology domain-containing family O 1 Protein
Recombinant Pleckstrin homology domain-containing family O 1 Protein Cat#
PA0200
Pleckstrin homology domain-containing family O 1 Protein Source
Recombinant protein.
Recombinant Pleckstrin homology domain-containing family O 1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pleckstrin homology domain-containing family O 1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pleckstrin homology domain-containing family O 1 Protein Activity
N/A
Recombinant protein Tag
Recombinant Pleckstrin homology domain-containing family O 1 Contains A 6x histidine tag
Recombinant Pleckstrin homology domain-containing family O 1 Protein Formulation
Liquid
Recombinant Pleckstrin homology domain-containing family O 1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Pleckstrin homology domain-containing family O 1 Protein or cDNA
Pleckstrin homology domain-containing family O 1 Protein family
-
Pleckstrin homology domain-containing family O 1 Subcellular locations
Cell membrane. Nucleus. Cytoplasm.
Pleckstrin homology domain-containing family O 1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP
by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1
activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.
Pleckstrin homology domain-containing family O 1 Sequence databases
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
