Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant Tribbles homolog 3 Protein
Recombinant Tribbles homolog 3 Protein Cat#
PW0215
Tribbles homolog 3 Protein Source
Recombinant protein.
Recombinant Tribbles homolog 3 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Tribbles homolog 3 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Tribbles homolog 3 Protein Activity
N/A
Recombinant protein Tag
Recombinant Tribbles homolog 3 Contains A 6x histidine tag
Recombinant Tribbles homolog 3 Protein Formulation
Liquid
Recombinant Tribbles homolog 3 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Tribbles homolog 3 Protein or cDNA
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, Tribbles subfamily
Tribbles homolog 3 Subcellular locations
Nucleus.
Tribbles homolog 3 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity. Interacts with MAPK kinases and regulates activation of MAP kinases. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. Does not display kinase activity.
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
