Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant TNF 1-receptor-associated factor 6 Protein
Recombinant TNF 1-receptor-associated factor 6 Protein Cat#
PA0236
TNF 1-receptor-associated factor 6 Protein Source
Recombinant protein.
Recombinant TNF 1-receptor-associated factor 6 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TNF 1-receptor-associated factor 6 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TNF 1-receptor-associated factor 6 Protein Activity
N/A
Recombinant protein Tag
Recombinant TNF 1-receptor-associated factor 6 Contains A 6x histidine tag
Recombinant TNF 1-receptor-associated factor 6 Protein Formulation
Liquid
Recombinant TNF 1-receptor-associated factor 6 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant TNF 1-receptor-associated factor 6 Protein or cDNA
TNF 1-receptor-associated factor 6 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin
chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-
Myb-mediated transactivation, in B lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor.
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)