Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Cell adhesion molecule 1 Protein
Recombinant Cell adhesion molecule 1 Protein Cat#
PA0033
Cell adhesion molecule 1 Protein Source
Recombinant protein.
Recombinant Cell adhesion molecule 1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Cell adhesion molecule 1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Cell adhesion molecule 1 Protein Activity
N/A
Recombinant protein Tag
Recombinant Cell adhesion molecule 1 Contains A 6x histidine tag
Recombinant Cell adhesion molecule 1 Protein Formulation
Liquid
Recombinant Cell adhesion molecule 1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Cell adhesion molecule 1 Protein or cDNA
Cell membrane; Single-pass type I membrane protein.
Cell adhesion molecule 1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer
(NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May
contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast
cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the
spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
