Human HLA class II histocompatibility antigen DRB5 beta (aa 30-227)
HLA class II histocompatibility antigen DRB5 beta Swiss Prot#
Q30154
HLA class II histocompatibility antigen DRB5 beta Protein names
HLA class II histocompatibility antigen, DRB5 beta chain (DR beta-5) (DR2-beta-2) (Dw2)
HLA class II histocompatibility antigen DRB5 beta Gene names
HLA-DRB5
Organism
Human
HLA class II histocompatibility antigen DRB5 beta Entry name
DRB5_HUMAN
HLA class II histocompatibility antigen DRB5 beta Codon optimized cDNA Clone
HLA class II histocompatibility antigen DRB5 beta CDNA Cat#
RPW0049
cDNA Tag
cDNA HLA class II histocompatibility antigen DRB5 beta Contains A 6x histidine tag
Condon optimized HLA class II histocompatibility antigen DRB5 beta CDNA Formulation
Liquid
Condon optimized HLA class II histocompatibility antigen DRB5 beta cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized HLA class II histocompatibility antigen DRB5 beta cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Cat#
PW0049
HLA class II histocompatibility antigen DRB5 beta Protein Source
Recombinant protein.
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Activity
N/A
Recombinant protein Tag
Recombinant HLA class II histocompatibility antigen DRB5 beta Contains A 6x histidine tag
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Formulation
Liquid
Recombinant HLA class II histocompatibility antigen DRB5 beta Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant HLA class II histocompatibility antigen DRB5 beta Protein or cDNA
HLA class II histocompatibility antigen DRB5 beta Protein family
MHC class II family
HLA class II histocompatibility antigen DRB5 beta Subcellular locations
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus > trans-Golgi network membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane pr
HLA class II histocompatibility antigen DRB5 beta FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accomodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components.
HLA class II histocompatibility antigen DRB5 beta Sequence databases
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
