Human C-type lectin domain family 7 member A (aa 1-247)
C-type lectin domain family 7 member A Swiss Prot#
Q9BXN2
C-type lectin domain family 7 member A Protein names
C-type lectin domain family 7 member A (Dendritic cell-associated C-type lectin 1) (DC-associated C-type lectin 1) (Dectin-1) (Beta-glucan 1-receptor) (C-type lectin superfamily member 12)
C-type lectin domain family 7 member A Gene names
CLEC7A (BGR) (CLECSF12) (DECTIN1) (UNQ539/PRO1082)
Organism
Human
C-type lectin domain family 7 member A Entry name
CLC7A_HUMAN
C-type lectin domain family 7 member A Codon optimized cDNA Clone
C-type lectin domain family 7 member A CDNA Cat#
RPA0059
cDNA Tag
cDNA C-type lectin domain family 7 member A Contains A 6x histidine tag
Condon optimized C-type lectin domain family 7 member A CDNA Formulation
Liquid
Condon optimized C-type lectin domain family 7 member A cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized C-type lectin domain family 7 member A cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant C-type lectin domain family 7 member A Protein
Recombinant C-type lectin domain family 7 member A Protein Cat#
PA0059
C-type lectin domain family 7 member A Protein Source
Recombinant protein.
Recombinant C-type lectin domain family 7 member A Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant C-type lectin domain family 7 member A Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant C-type lectin domain family 7 member A Protein Activity
N/A
Recombinant protein Tag
Recombinant C-type lectin domain family 7 member A Contains A 6x histidine tag
Recombinant C-type lectin domain family 7 member A Protein Formulation
Liquid
Recombinant C-type lectin domain family 7 member A Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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C-type lectin domain family 7 member A Protein family
-
C-type lectin domain family 7 member A Subcellular locations
Membrane; Single-pass type II membrane protein. Cytoplasm.
C-type lectin domain family 7 member A FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2- mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not

involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
C-type lectin domain family 7 member A Sequence databases
EMBL DDBJ GenBank
C-type lectin domain family 7 member A 3D structure databases
ModBase
C-type lectin domain family 7 member A Protein-protein interaction databases
STRING
C-type lectin domain family 7 member A Proteomic databases
PRIDE
C-type lectin domain family 7 member A Genome annotation databases
Ensembl GeneID KEGG UCSC
C-type lectin domain family 7 member A Organism specific databases
CTD MGI
C-type lectin domain family 7 member A Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
C-type lectin domain family 7 member A Gene expression databases
Bgee ArrayExpress Genevestigator
C-type lectin domain family 7 member A Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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