Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant COP9 signalosome complex subunit 6 Protein
Recombinant COP9 signalosome complex subunit 6 Protein Cat#
PW0068
COP9 signalosome complex subunit 6 Protein Source
Recombinant protein.
Recombinant COP9 signalosome complex subunit 6 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant COP9 signalosome complex subunit 6 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant COP9 signalosome complex subunit 6 Protein Activity
N/A
Recombinant protein Tag
Recombinant COP9 signalosome complex subunit 6 Contains A 6x histidine tag
Recombinant COP9 signalosome complex subunit 6 Protein Formulation
Liquid
Recombinant COP9 signalosome complex subunit 6 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant COP9 signalosome complex subunit 6 Protein or cDNA
COP9 signalosome complex subunit 6 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN,
IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
