Mouse Suppressor of cytokine signaling 5 (aa 1-536)
Suppressor of cytokine signaling 5 Swiss Prot#
O54928
Suppressor of cytokine signaling 5 Protein names
Suppressor of cytokine signaling 5 (SOCS-5) (Cytokine-inducible SH2-containing protein 5)
Suppressor of cytokine signaling 5 Gene names
Socs5 (Cish5)
Organism
Mouse
Suppressor of cytokine signaling 5 Entry name
SOCS5_MOUSE
Suppressor of cytokine signaling 5 Codon optimized cDNA Clone
Suppressor of cytokine signaling 5 CDNA Cat#
RPA0692
cDNA Tag
cDNA Suppressor of cytokine signaling 5 Contains A 6x histidine tag
Condon optimized Suppressor of cytokine signaling 5 CDNA Formulation
Liquid
Condon optimized Suppressor of cytokine signaling 5 cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Suppressor of cytokine signaling 5 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Suppressor of cytokine signaling 5 Protein
Recombinant Suppressor of cytokine signaling 5 Protein Cat#
PA0692
Suppressor of cytokine signaling 5 Protein Source
Recombinant protein.
Recombinant Suppressor of cytokine signaling 5 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Suppressor of cytokine signaling 5 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Suppressor of cytokine signaling 5 Protein Activity
N/A
Recombinant protein Tag
Recombinant Suppressor of cytokine signaling 5 Contains A 6x histidine tag
Recombinant Suppressor of cytokine signaling 5 Protein Formulation
Liquid
Recombinant Suppressor of cytokine signaling 5 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Suppressor of cytokine signaling 5 Protein or cDNA
Suppressor of cytokine signaling 5 Subcellular locations
-
Suppressor of cytokine signaling 5 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS5 is involved in regulating T-helper cell differentiation by inhibition of the IL4 signaling pathway which
promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the
ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Suppressor of cytokine signaling 5 Sequence databases
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
