Human Polycomb group RING finger protein 2 (aa 1-344)
Polycomb group RING finger protein 2 Swiss Prot#
P35227
Polycomb group RING finger protein 2 Protein names
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Polycomb group RING finger protein 2 Gene names
PCGF2 (MEL18) (RNF110) (ZNF144)
Organism
Human
Polycomb group RING finger protein 2 Entry name
PCGF2_HUMAN
Polycomb group RING finger protein 2 Codon optimized cDNA Clone
Polycomb group RING finger protein 2 CDNA Cat#
RPW0075
cDNA Tag
cDNA Polycomb group RING finger protein 2 Contains A 6x histidine tag
Condon optimized Polycomb group RING finger protein 2 CDNA Formulation
Liquid
Condon optimized Polycomb group RING finger protein 2 cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Polycomb group RING finger protein 2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant Polycomb group RING finger protein 2 Protein
Recombinant Polycomb group RING finger protein 2 Protein Cat#
PW0075
Polycomb group RING finger protein 2 Protein Source
Recombinant protein.
Recombinant Polycomb group RING finger protein 2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Polycomb group RING finger protein 2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Polycomb group RING finger protein 2 Protein Activity
N/A
Recombinant protein Tag
Recombinant Polycomb group RING finger protein 2 Contains A 6x histidine tag
Recombinant Polycomb group RING finger protein 2 Protein Formulation
Liquid
Recombinant Polycomb group RING finger protein 2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Polycomb group RING finger protein 2 Protein or cDNA
Polycomb group RING finger protein 2 Protein family
-
Polycomb group RING finger protein 2 Subcellular locations
Nucleus.
Polycomb group RING finger protein 2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cells by maintaining expression of HES1. Also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. Component of the Polycomb group
(PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of
histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Polycomb group RING finger protein 2 Sequence databases
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
