Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Cat#
PA0836
Heterogeneous nuclear ribonucleoprotein D0 Protein Source
Recombinant protein.
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Activity
N/A
Recombinant protein Tag
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Contains A 6x histidine tag
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Formulation
Liquid
Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Heterogeneous nuclear ribonucleoprotein D0 Protein or cDNA
Heterogeneous nuclear ribonucleoprotein D0 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and
functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA
oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation.
May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
