DNA dC->dU-editing enzyme APOBEC-3G Codon optimized cDNA Clone
DNA dC->dU-editing enzyme APOBEC-3G CDNA Cat#
RPW0085
cDNA Tag
cDNA DNA dC->dU-editing enzyme APOBEC-3G Contains A 6x histidine tag
Condon optimized DNA dC->dU-editing enzyme APOBEC-3G CDNA Formulation
Liquid
Condon optimized DNA dC->dU-editing enzyme APOBEC-3G cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized DNA dC->dU-editing enzyme APOBEC-3G cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Cat#
PW0085
DNA dC->dU-editing enzyme APOBEC-3G Protein Source
Recombinant protein.
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Activity
N/A
Recombinant protein Tag
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Contains A 6x histidine tag
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Formulation
Liquid
Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant DNA dC->dU-editing enzyme APOBEC-3G Protein or cDNA
DNA dC->dU-editing enzyme APOBEC-3G Protein family
Cytidine and deoxycytidylate deaminase family
DNA dC->dU-editing enzyme APOBEC-3G Subcellular locations
Cytoplasm. Nucleus.
DNA dC->dU-editing enzyme APOBEC-3G FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: DNA deaminase (cytidine deaminase) that mediates a form of innate resistance to retroviral infections (at least to HIV-1 infection) by triggering G-to-A hypermutation in the newly synthesized viral DNA. The replacements C-to-U in
the minus strand DNA of HIV-1 during reverse transcription, leads to G-to-A transitions in the plus strand. The inhibition of viral replication is either due to the degradation of the minus strand before its integration or to the lethality of the
hypermutations. Modification of both DNA strands is not excluded. This antiviral activity is neutralized by the virion infectivity factor (VIF), that prevents the incorporation of APOBEC3G into progeny HIV-1 virions by both inhibiting its
translation and/or by inducing its ubiquitination and subsequent degradation by the 26S proteasome. APOBEC3G binds a variety of RNAs, but does not display detectable APOB, NF1 and NAT1 mRNA editing.
DNA dC->dU-editing enzyme APOBEC-3G Sequence databases
For cDNA or Recombinant Protein Search ( Input Cat#, or Gene name, or Protein Name, or Accession Number, or the first 60 amino acids sequence from Met)
