Rat Platelet-derived growth factor C (aa 23-345)
Platelet-derived growth factor C Swiss Prot#
Q9EQX6
Platelet-derived growth factor C Protein names
Platelet-derived growth factor C (PDGF-C) (Spinal cord-derived growth factor) (rScdfg) (Fallotein) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form) Platelet-derived growth factor C, 1-receptor-binding form (PDGFC 1
Platelet-derived growth factor C Gene names
Pdgfc (Scdgf)
Organism
Rat
Platelet-derived growth factor C Entry name
PDGFC_RAT
Platelet-derived growth factor C Codon optimized cDNA Clone
Platelet-derived growth factor C CDNA Cat#
RPA0889
cDNA Tag
cDNA Platelet-derived growth factor C Contains A 6x histidine tag
Condon optimized Platelet-derived growth factor C CDNA Formulation
Liquid
Condon optimized Platelet-derived growth factor C cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Platelet-derived growth factor C cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Platelet-derived growth factor C Protein
Recombinant Platelet-derived growth factor C Protein Cat#
PA0889
Platelet-derived growth factor C Protein Source
Recombinant protein.
Recombinant Platelet-derived growth factor C Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Platelet-derived growth factor C Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Platelet-derived growth factor C Protein Activity
N/A
Recombinant protein Tag
Recombinant Platelet-derived growth factor C Contains A 6x histidine tag
Recombinant Platelet-derived growth factor C Protein Formulation
Liquid
Recombinant Platelet-derived growth factor C Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Platelet-derived growth factor C Protein or cDNA
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Platelet-derived growth factor C Protein family
PDGF/VEGF growth factor family
Platelet-derived growth factor C Subcellular locations
Cytoplasm. Secreted. Nucleus. Cytoplasmic granule.
Platelet-derived growth factor C FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Potent mitogen and chemoattractant for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. Appears to be involved in the three stages of wound healing: inflammation, proliferation and remodeling. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. Acts as a specific ligand for alpha platelet-derived growth

factor receptor homodimer, and alpha and beta heterodimer. Binding to receptors induces their activation by tyrosine phosphorylation. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the

maintainance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function. Seems to be involved in palatogenesis (By similarity).
Platelet-derived growth factor C Sequence databases
EMBL DDBJ GenBank
Platelet-derived growth factor C 3D structure databases
ModBase
Platelet-derived growth factor C Protein-protein interaction databases
STRING
Platelet-derived growth factor C Proteomic databases
PRIDE
Platelet-derived growth factor C Genome annotation databases
Ensembl GeneID KEGG UCSC
Platelet-derived growth factor C Organism specific databases
CTD MGI
Platelet-derived growth factor C Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Platelet-derived growth factor C Gene expression databases
Bgee ArrayExpress Genevestigator
Platelet-derived growth factor C Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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