Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to
restore the loss-of-function.
Recombinant WW domain-containing transcription regulator 1 Protein
Recombinant WW domain-containing transcription regulator 1 Protein Cat#
PW0090
WW domain-containing transcription regulator 1 Protein Source
Recombinant protein.
Recombinant WW domain-containing transcription regulator 1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant WW domain-containing transcription regulator 1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant WW domain-containing transcription regulator 1 Protein Activity
N/A
Recombinant protein Tag
Recombinant WW domain-containing transcription regulator 1 Contains A 6x histidine tag
Recombinant WW domain-containing transcription regulator 1 Protein Formulation
Liquid
Recombinant WW domain-containing transcription regulator 1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant WW domain-containing transcription regulator 1 Protein or cDNA
WW domain-containing transcription regulator 1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The
core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and
inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator
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