Rat Serglycin (aa 27-179)
Serglycin Swiss Prot#
P04917
Serglycin Protein names
Serglycin (Secretory granule proteoglycan core protein) (Chondroitin sulfate proteoglycan core protein) (Proteoglycan 10K core protein) (PG19 core protein) (Cytolytic granule proteoglycan core protein)
Serglycin Gene names
Srgn (Pgsg) (Prg) (Prg1)
Organism
Rat
Serglycin Entry name
SRGN_RAT
Serglycin Codon optimized cDNA Clone
Serglycin CDNA Cat#
RPA0917
cDNA Tag
cDNA Serglycin Contains A 6x histidine tag
Condon optimized Serglycin CDNA Formulation
Liquid
Condon optimized Serglycin cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Serglycin cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Serglycin Protein
Recombinant Serglycin Protein Cat#
PA0917
Serglycin Protein Source
Recombinant protein.
Recombinant Serglycin Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Serglycin Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Serglycin Protein Activity
N/A
Recombinant protein Tag
Recombinant Serglycin Contains A 6x histidine tag
Recombinant Serglycin Protein Formulation
Liquid
Recombinant Serglycin Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Serglycin Protein family
Serglycin family
Serglycin Subcellular locations
Cytoplasmic granule. Secreted > extracellular space. Golgi apparatus.
Serglycin FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B

which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization (By similarity).
Serglycin Sequence databases
EMBL DDBJ GenBank
Serglycin 3D structure databases
ModBase
Serglycin Protein-protein interaction databases
STRING
Serglycin Proteomic databases
PRIDE
Serglycin Genome annotation databases
Ensembl GeneID KEGG UCSC
Serglycin Organism specific databases
CTD MGI
Serglycin Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Serglycin Gene expression databases
Bgee ArrayExpress Genevestigator
Serglycin Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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