Human Phosphatidylcholine-sterol acyltransferase (aa 25-440)
Phosphatidylcholine-sterol acyltransferase Swiss Prot#
P04180
Phosphatidylcholine-sterol acyltransferase Protein names
Phosphatidylcholine-sterol acyltransferase (EC 2.3.1.43) (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
Phosphatidylcholine-sterol acyltransferase Gene names
LCAT
Organism
Human
Phosphatidylcholine-sterol acyltransferase Entry name
LCAT_HUMAN
Phosphatidylcholine-sterol acyltransferase Codon optimized cDNA Clone
Phosphatidylcholine-sterol acyltransferase CDNA Cat#
RPW0092
cDNA Tag
cDNA Phosphatidylcholine-sterol acyltransferase Contains A 6x histidine tag
Condon optimized Phosphatidylcholine-sterol acyltransferase CDNA Formulation
Liquid
Condon optimized Phosphatidylcholine-sterol acyltransferase cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Phosphatidylcholine-sterol acyltransferase cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Phosphatidylcholine-sterol acyltransferase Protein
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Cat#
PW0092
Phosphatidylcholine-sterol acyltransferase Protein Source
Recombinant protein.
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Activity
N/A
Recombinant protein Tag
Recombinant Phosphatidylcholine-sterol acyltransferase Contains A 6x histidine tag
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Formulation
Liquid
Recombinant Phosphatidylcholine-sterol acyltransferase Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Phosphatidylcholine-sterol acyltransferase Protein or cDNA
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Phosphatidylcholine-sterol acyltransferase Protein family
AB hydrolase superfamily, Lipase family
Phosphatidylcholine-sterol acyltransferase Subcellular locations
Secreted.
Phosphatidylcholine-sterol acyltransferase FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.
Phosphatidylcholine-sterol acyltransferase Sequence databases
EMBL DDBJ GenBank
Phosphatidylcholine-sterol acyltransferase 3D structure databases
ModBase
Phosphatidylcholine-sterol acyltransferase Protein-protein interaction databases
STRING
Phosphatidylcholine-sterol acyltransferase Proteomic databases
PRIDE
Phosphatidylcholine-sterol acyltransferase Genome annotation databases
Ensembl GeneID KEGG UCSC
Phosphatidylcholine-sterol acyltransferase Organism specific databases
CTD MGI
Phosphatidylcholine-sterol acyltransferase Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Phosphatidylcholine-sterol acyltransferase Gene expression databases
Bgee ArrayExpress Genevestigator
Phosphatidylcholine-sterol acyltransferase Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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