Rat Tyrosine phosphatase non-1-receptor type 1 (aa 32-509)
Tyrosine phosphatase non-1-receptor type 1 Swiss Prot#
P97710
Tyrosine phosphatase non-1-receptor type 1 Protein names
Tyrosine-protein phosphatase non-1-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Inhibitory 1-receptor SHPS-1) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (Macrophage fusi
Tyrosine phosphatase non-1-receptor type 1 Gene names
Sirpa (Bit) (Mfr) (Ptpns1) (Shps1) (Sirp)
Organism
Rat
Tyrosine phosphatase non-1-receptor type 1 Entry name
SHPS1_RAT
Tyrosine phosphatase non-1-receptor type 1 Codon optimized cDNA Clone
Tyrosine phosphatase non-1-receptor type 1 CDNA Cat#
RPA0940
cDNA Tag
cDNA Tyrosine phosphatase non-1-receptor type 1 Contains A 6x histidine tag
Condon optimized Tyrosine phosphatase non-1-receptor type 1 CDNA Formulation
Liquid
Condon optimized Tyrosine phosphatase non-1-receptor type 1 cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Tyrosine phosphatase non-1-receptor type 1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Cat#
PA0940
Tyrosine phosphatase non-1-receptor type 1 Protein Source
Recombinant protein.
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Activity
N/A
Recombinant protein Tag
Recombinant Tyrosine phosphatase non-1-receptor type 1 Contains A 6x histidine tag
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Formulation
Liquid
Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Tyrosine phosphatase non-1-receptor type 1 Protein or cDNA
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Tyrosine phosphatase non-1-receptor type 1 Protein family
-
Tyrosine phosphatase non-1-receptor type 1 Subcellular locations
Membrane; Single-pass type I membrane protein.
Tyrosine phosphatase non-1-receptor type 1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell

adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature

dendritic cells. May play a role in the release of nitric oxide by macrophages (By similarity).
Tyrosine phosphatase non-1-receptor type 1 Sequence databases
EMBL DDBJ GenBank
Tyrosine phosphatase non-1-receptor type 1 3D structure databases
ModBase
Tyrosine phosphatase non-1-receptor type 1 Protein-protein interaction databases
STRING
Tyrosine phosphatase non-1-receptor type 1 Proteomic databases
PRIDE
Tyrosine phosphatase non-1-receptor type 1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Tyrosine phosphatase non-1-receptor type 1 Organism specific databases
CTD MGI
Tyrosine phosphatase non-1-receptor type 1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Tyrosine phosphatase non-1-receptor type 1 Gene expression databases
Bgee ArrayExpress Genevestigator
Tyrosine phosphatase non-1-receptor type 1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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