Human ICOS ligand (aa 19-302)
ICOS ligand Swiss Prot#
O75144
ICOS ligand Protein names
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
ICOS ligand Gene names
ICOSLG (B7H2) (B7RP1) (ICOSL) (KIAA0653)
Organism
Human
ICOS ligand Entry name
ICOSL_HUMAN
ICOS ligand Codon optimized cDNA Clone
ICOS ligand CDNA Cat#
RPA0096
cDNA Tag
cDNA ICOS ligand Contains A 6x histidine tag
Condon optimized ICOS ligand CDNA Formulation
Liquid
Condon optimized ICOS ligand cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized ICOS ligand cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant ICOS ligand Protein
Recombinant ICOS ligand Protein Cat#
PA0096
ICOS ligand Protein Source
Recombinant protein.
Recombinant ICOS ligand Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant ICOS ligand Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant ICOS ligand Protein Activity
N/A
Recombinant protein Tag
Recombinant ICOS ligand Contains A 6x histidine tag
Recombinant ICOS ligand Protein Formulation
Liquid
Recombinant ICOS ligand Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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ICOS ligand Protein family
Immunoglobulin superfamily, BTN/MOG family
ICOS ligand Subcellular locations
Membrane; Single-pass type I membrane protein.
ICOS ligand FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
ICOS ligand Sequence databases
EMBL DDBJ GenBank
ICOS ligand 3D structure databases
ModBase
ICOS ligand Protein-protein interaction databases
STRING
ICOS ligand Proteomic databases
PRIDE
ICOS ligand Genome annotation databases
Ensembl GeneID KEGG UCSC
ICOS ligand Organism specific databases
CTD MGI
ICOS ligand Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ICOS ligand Gene expression databases
Bgee ArrayExpress Genevestigator
ICOS ligand Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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