Human Vacuolar protein sorting-associated protein 4A (aa 1-437)
Vacuolar protein sorting-associated protein 4A Swiss Prot#
Q9UN37
Vacuolar protein sorting-associated protein 4A Protein names
Vacuolar protein sorting-associated protein 4A (VPS4-1) (hVPS4) (Protein SKD2)
Vacuolar protein sorting-associated protein 4A Gene names
VPS4A (VPS4)
Organism
Human
Vacuolar protein sorting-associated protein 4A Entry name
VPS4A_HUMAN
Vacuolar protein sorting-associated protein 4A Codon optimized cDNA Clone
Vacuolar protein sorting-associated protein 4A CDNA Cat#
RPW0097
cDNA Tag
cDNA Vacuolar protein sorting-associated protein 4A Contains A 6x histidine tag
Condon optimized Vacuolar protein sorting-associated protein 4A CDNA Formulation
Liquid
Condon optimized Vacuolar protein sorting-associated protein 4A cDNA Storage
Ship at Room temperature.. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized Vacuolar protein sorting-associated protein 4A cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Vacuolar protein sorting-associated protein 4A Protein
Recombinant Vacuolar protein sorting-associated protein 4A Protein Cat#
PW0097
Vacuolar protein sorting-associated protein 4A Protein Source
Recombinant protein.
Recombinant Vacuolar protein sorting-associated protein 4A Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Vacuolar protein sorting-associated protein 4A Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Vacuolar protein sorting-associated protein 4A Protein Activity
N/A
Recombinant protein Tag
Recombinant Vacuolar protein sorting-associated protein 4A Contains A 6x histidine tag
Recombinant Vacuolar protein sorting-associated protein 4A Protein Formulation
Liquid
Recombinant Vacuolar protein sorting-associated protein 4A Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Vacuolar protein sorting-associated protein 4A Protein or cDNA
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Vacuolar protein sorting-associated protein 4A Protein family
AAA ATPase family
Vacuolar protein sorting-associated protein 4A Subcellular locations
Prevacuolar compartment membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein.
Vacuolar protein sorting-associated protein 4A FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis.
Vacuolar protein sorting-associated protein 4A Sequence databases
EMBL DDBJ GenBank
Vacuolar protein sorting-associated protein 4A 3D structure databases
ModBase
Vacuolar protein sorting-associated protein 4A Protein-protein interaction databases
STRING
Vacuolar protein sorting-associated protein 4A Proteomic databases
PRIDE
Vacuolar protein sorting-associated protein 4A Genome annotation databases
Ensembl GeneID KEGG UCSC
Vacuolar protein sorting-associated protein 4A Organism specific databases
CTD MGI
Vacuolar protein sorting-associated protein 4A Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Vacuolar protein sorting-associated protein 4A Gene expression databases
Bgee ArrayExpress Genevestigator
Vacuolar protein sorting-associated protein 4A Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY

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