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| Human cd126 (aa 20 – 365) |
| CD126 Swiss Prot | | P08887 |
| CD126 Protein names | | Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) |
| CD126 Gene names | | IL6R |
| Organism | | Human |
| CD126 Entry name | | IL6RA_HUMAN |
| CD126 Codon optimized cDNA Clone |
| CD126 cDNA Cat | | RPV0101 |
| cDNA Tag | | cDNA CD126 contains A 6x histidine tag |
| Condon optimized CD126 cDNA Formulation | | Liquid |
| Condon optimized CD126 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD126 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD126 Protein |
| Recombinant CD126 Protein Cat | | PV0101 |
| CD126 Protein Source | | Recombinant protein |
| Recombinant CD126 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD126 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD126 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD126 contains A 6x histidine tag |
| Recombinant CD126 Protein Formulation | | Liquid |
| Recombinant CD126 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD126 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD126 SUBUNIT | | SUBUNIT: Hexamer of two molecules each of IL6, IL6R and IL6ST. |
| CD126 Subcellular locations | | SUBCELLULAR LOCATION: Isoform 1: Basolateral cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Secreted. |
| CD126 FUNCTION According to UniProtKB Swiss Prot | | Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.; Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. |
| CD126 Sequence databases | | EMBL | DDBJ | GenBank |
| CD126 3D structure databases | | ModBase |
| CD126 Protein protein interaction databases | | STRING |
| CD126 Proteomic databases | | PRIDE |
| CD126 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD126 Organism specific databases | | CTD | MGI |
| CD126 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD126 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD126 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
