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| Human cd14 (aa 20 – 367) |
| CD14 Swiss Prot | | P08571 |
| CD14 Protein names | | Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form] |
| CD14 Gene names | | CD14 |
| Organism | | Human |
| CD14 Entry name | | CD14_HUMAN |
| CD14 Codon optimized cDNA Clone |
| CD14 cDNA Cat | | RPV0136 |
| cDNA Tag | | cDNA CD14 contains A 6x histidine tag |
| Condon optimized CD14 cDNA Formulation | | Liquid |
| Condon optimized CD14 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD14 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD14 Protein |
| Recombinant CD14 Protein Cat | | PV0136 |
| CD14 Protein Source | | Recombinant protein |
| Recombinant CD14 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD14 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD14 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD14 contains A 6x histidine tag |
| Recombinant CD14 Protein Formulation | | Liquid |
| Recombinant CD14 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD14 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD14 SUBUNIT | | SUBUNIT: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4. |
| CD14 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. |
| CD14 FUNCTION According to UniProtKB Swiss Prot | | Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules. |
| CD14 Sequence databases | | EMBL | DDBJ | GenBank |
| CD14 3D structure databases | | ModBase |
| CD14 Protein protein interaction databases | | STRING |
| CD14 Proteomic databases | | PRIDE |
| CD14 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD14 Organism specific databases | | CTD | MGI |
| CD14 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD14 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD14 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |