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Human cd140b (aa 33 – 531)

CD140b Swiss Prot

P09619

CD140b Protein names

Beta-type platelet-derived growth factor receptor (PDGF-R-beta) (EC 2.7.10.1) (CD140 antigen-like family member B) (CD antigen CD140b)

CD140b Gene names

PDGFRB

Organism

Human

CD140b Entry name

PGFRB_HUMAN

CD140b Codon optimized cDNA Clone

CD140b cDNA Cat

RPV0142

cDNA Tag

cDNA CD140b contains A 6x histidine tag

Condon optimized CD140b cDNA Formulation

Liquid

Condon optimized CD140b cDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Condon optimized CD140b cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.

Recombinant CD140b Protein

Recombinant CD140b Protein Cat

PV0142

CD140b Protein Source

Recombinant protein

Recombinant CD140b Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant CD140b Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant CD140b Protein Activity

N/A

Recombinant protein Tag

Recombinant CD140b contains A 6x histidine tag

Recombinant CD140b Protein Formulation

Liquid

Recombinant CD140b Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CD140b SUBUNIT

SUBUNIT: Homodimer, and heterodimer with PDGFRA. Interacts with APS. The autophosphorylated form interacts directly with SHB and with PIK3C2B, maybe indirectly. Interacts with GRB10.

CD140b Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

CD140b FUNCTION According to UniProtKB Swiss Prot

Receptor that binds specifically to PDGFB and PDGFD and has a tyrosine-protein kinase activity. Phosphorylates Tyr residues at the C-terminus of PTPN11 creating a binding site for the SH2 domain of GRB2.

CD140b Sequence databases

EMBL

DDBJ

GenBank

CD140b 3D structure databases

ModBase

CD140b Protein protein interaction databases

STRING

CD140b Proteomic databases

PRIDE

CD140b Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

CD140b Organism specific databases

CTD

MGI

CD140b Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD140b Gene expression databases

Bgee

ArrayExpress

Genevestigator

CD140b Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY