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| Human cd144 (aa 48 – 599) |
| CD144 Swiss Prot | | P33151 |
| CD144 Protein names | | Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144) |
| CD144 Gene names | | CDH5 |
| Organism | | Human |
| CD144 Entry name | | CADH5_HUMAN |
| CD144 Codon optimized cDNA Clone |
| CD144 cDNA Cat | | RPV0154 |
| cDNA Tag | | cDNA CD144 contains A 6x histidine tag |
| Condon optimized CD144 cDNA Formulation | | Liquid |
| Condon optimized CD144 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD144 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD144 Protein |
| Recombinant CD144 Protein Cat | | PV0154 |
| CD144 Protein Source | | Recombinant protein |
| Recombinant CD144 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD144 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD144 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD144 contains A 6x histidine tag |
| Recombinant CD144 Protein Formulation | | Liquid |
| Recombinant CD144 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD144 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD144 SUBUNIT | | SUBUNIT: Interacts via cadherin 5 domain with PTPRB (By similarity). Interacts with TRPC4. Interacts with KRIT1. |
| CD144 Subcellular locations | | SUBCELLULAR LOCATION: Cell junction. Cell membrane; Single-pass type I membrane protein (Probable). Note=Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. |
| CD144 FUNCTION According to UniProtKB Swiss Prot | | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and |
| | maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, |
| | PARD3, TIAM1 and RAP1B to the cell junction. |
| CD144 Sequence databases | | EMBL | DDBJ | GenBank |
| CD144 3D structure databases | | ModBase |
| CD144 Protein protein interaction databases | | STRING |
| CD144 Proteomic databases | | PRIDE |
| CD144 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD144 Organism specific databases | | CTD | MGI |
| CD144 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD144 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD144 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
