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| Rat cd146 (aa 24 – 560) |
| CD146 Swiss Prot | | Q9EPF2 |
| CD146 Protein names | | Cell surface glycoprotein MUC18 (Gicerin) (Melanoma cell adhesion molecule) (Melanoma-associated antigen MUC18) (CD antigen CD146) |
| CD146 Gene names | | Mcam Muc18 |
| Organism | | Rat |
| CD146 Entry name | | MUC18_RAT |
| CD146 Codon optimized cDNA Clone |
| CD146 cDNA Cat | | RPV0159 |
| cDNA Tag | | cDNA CD146 contains A 6x histidine tag |
| Condon optimized CD146 cDNA Formulation | | Liquid |
| Condon optimized CD146 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD146 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD146 Protein |
| Recombinant CD146 Protein Cat | | PV0159 |
| CD146 Protein Source | | Recombinant protein |
| Recombinant CD146 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD146 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD146 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD146 contains A 6x histidine tag |
| Recombinant CD146 Protein Formulation | | Liquid |
| Recombinant CD146 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD146 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD146 SUBUNIT | | - |
| CD146 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Perikaryon. Note=Detected at the surface of the cell body of motor neurons. |
| CD146 FUNCTION According to UniProtKB Swiss Prot | | Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular |
| | calcium concentration (By similarity). |
| CD146 Sequence databases | | EMBL | DDBJ | GenBank |
| CD146 3D structure databases | | ModBase |
| CD146 Protein protein interaction databases | | STRING |
| CD146 Proteomic databases | | PRIDE |
| CD146 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD146 Organism specific databases | | CTD | MGI |
| CD146 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD146 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD146 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
