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Human cd152 (aa 36 – 161)
CD152 Swiss Prot
P16410
CD152 Protein names
Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)
CD152 Gene names
CTLA4 CD152
Organism
Human
CD152 Entry name
CTLA4_HUMAN
CD152 Codon optimized cDNA Clone
CD152 cDNA Cat
RPV0171
cDNA Tag
cDNA CD152 contains A 6x histidine tag
Condon optimized CD152 cDNA Formulation
Liquid
Condon optimized CD152 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD152 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD152 Protein
Recombinant CD152 Protein Cat
PV0171
CD152 Protein Source
Recombinant protein
Recombinant CD152 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD152 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD152 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD152 contains A 6x histidine tag
Recombinant CD152 Protein Formulation
Liquid
Recombinant CD152 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD152 SUBUNIT
SUBUNIT: Homodimer; disulfide-linked. Binds to CD80/B7-1 and CD86/B7.2.
CD152 Subcellular locations
SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalisation;.
CD152 FUNCTION According to UniProtKB Swiss Prot
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
CD152 Sequence databases
EMBL DDBJ GenBank
CD152 3D structure databases
ModBase
CD152 Protein protein interaction databases
STRING
CD152 Proteomic databases
PRIDE
CD152 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD152 Organism specific databases
CTD MGI
CD152 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD152 Gene expression databases
Bgee ArrayExpress Genevestigator
CD152 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY