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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Antibody Immobilization
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Recombinant protein
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Mouse Nr1i2 (aa 1-431)
Nr1i2 Swiss Prot#
O54915
Nr1i2 protein names
Nuclear receptor subfamily 1 group I member 2 (Pregnane X receptor)

(Orphan nuclear receptor PXR)
Nr1i2 Gene names
Nr1i2 (Pxr)
Organism
Mouse
Nr1i2 Entry name
NR1I2_MOUSE
Nr1i2 Codon optimized cDNA Clone
Nr1i2 CDNA Cat#
RPR0197
cDNA Tag
cDNA Nr1i2 Contains A 6x histidine tag
Condon optimized Nr1i2 CDNA Formulation
Liquid
Condon optimized Nr1i2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized Nr1i2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Nr1i2 protein
Recombinant Nr1i2 protein Cat#
PR0197
Nr1i2 protein Source
Recombinant protein.
Recombinant Nr1i2 protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Nr1i2 protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Nr1i2 protein Activity
N/A
Recombinant protein Tag
Recombinant Nr1i2 contains A 6x histidine tag
Recombinant Nr1i2 protein Formulation
Liquid
Recombinant Nr1i2 protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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Nr1i2 protein family
Nuclear hormone receptor family, NR1 subfamily
Nr1i2 Subcellular locations
Nucleus.
Nr1i2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Nuclear receptor that binds and is activated by a variety of

endogenous and xenobiotic compounds. Transcription factor that activates

the transcription of multiple genes involved in the metabolism and

secretion of potentially harmful xenobiotics, endogenous compounds and

drugs. Response to specific ligands is species-specific, due to differences

in the ligand-binding domain. Binds to a response element in the promoters

of the CYP3A4 and ABCB1/MDR1 genes (By similarity). Activated by

naturally occurring steroids such as pregnenolone and progesterone, the

cholesterol metabolite 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol,

synthetic glucocorticoids and antiglucocorticoids and 16-alpha-carbonitrile

(PCN).
Nr1i2 Sequence databases
EMBL DDBJ GenBank
Nr1i2 3D structure databases
ModBase
Nr1i2 protein-protein interaction databases
STRING
Nr1i2 Proteomic databases
PRIDE
Nr1i2 Genome annotation databases
Ensembl GeneID KEGG UCSC
Nr1i2 Organism specific databases
CTD MGI
Nr1i2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Nr1i2 Gene expression databases
Bgee ArrayExpress Genevestigator
Nr1i2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY