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MouseHey2 (aa 1-339)

Hey2 Swiss Prot#

Q9QUS4

Hey2 Protein names

Hairy/enhancer-of-split related with YRPW motif protein 2 (Hairy and

enhancer of split-related protein 2) (HESR-2) (Hairy-related transcription

factor 2) (mHRT2) (HES-related repressor protein 2) (Protein gridlock

homolog)

Hey2 Gene names

Hey2 (Chf1) (Herp) (Herp1) (Hesr2) (Hrt2)

Organism

Mouse

Hey2 Entry name

HEY2_MOUSE

Hey2 Codon optimized cDNA Clone

Hey2 CDNA Cat#

RPU0204

cDNA Tag

cDNA Hey2 Contains A 6x histidine tag

Condon optimized Hey2 CDNA Formulation

Liquid

Condon optimized Hey2 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized Hey2 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Hey2 Protein

Recombinant Hey2 Protein Cat#

PU0204

Hey2 Protein Source

Recombinant protein.

Recombinant Hey2 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant Hey2 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant Hey2 Protein Activity

N/A

Recombinant protein Tag

Recombinant Hey2 contains A 6x histidine tag

Recombinant Hey2 Protein Formulation

Liquid

Recombinant Hey2 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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Hey2 Protein family

HEY family

Hey2 Subcellular locations

Nucleus.

Hey2 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Transcriptional repressor which functions as a downstream

effector of Notch signaling in cardiovascular development. Specifically

required for the Notch-induced endocardial epithelial to mesenchymal

transition, which is itself criticial for cardiac valve and septum

development. May be required in conjunction with HEY1 to specify arterial

cell fate or identity. Promotes maintenance of neuronal precursor cells and

glial versus neuronal fate specification. Binds preferentially to the

canonical E box sequence 5'-CACGTG-3'. Represses transcription by the

cardiac transcriptional activators GATA4 and GATA6 and by the neuronal

bHLH factors ASCL1/MASH1 and NEUROD4/MATH3.

Hey2 Sequence databases

EMBL

DDBJ

GenBank

Hey2 3D structure databases

ModBase

Hey2 Protein-protein interaction databases

STRING

Hey2 Proteomic databases

PRIDE

Hey2 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

Hey2 Organism specific databases

CTD

MGI

Hey2 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Hey2 Gene expression databases

Bgee

ArrayExpress

Genevestigator

Hey2 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY