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Magnetic Separator
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Human APTX (aa 1-356)
APTX Swiss Prot#
Q7Z2E3
APTX Protein names
Aprataxin (EC 3.-.-.-) (Forkhead-associated domain histidine triad-like

protein) (FHA-HIT)
APTX Gene names
APTX (AXA1)
Organism
Human
APTX Entry name
APTX_HUMAN
APTX Codon optimized cDNA Clone
APTX CDNA Cat#
RPT0205
cDNA Tag
cDNA APTX Contains A 6x histidine tag
Condon optimized APTX CDNA Formulation
Liquid
Condon optimized APTX CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized APTX cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant APTX Protein
Recombinant APTX Protein Cat#
PT0205
APTX Protein Source
Recombinant protein.
Recombinant APTX Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant APTX Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant APTX Protein Activity
N/A
Recombinant protein Tag
Recombinant APTX contains A 6x histidine tag
Recombinant APTX Protein Formulation
Liquid
Recombinant APTX Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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APTX Protein family
-
APTX Subcellular locations
Nucleus > nucleoplasm. Nucleus > nucleolus.
APTX FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: DNA-binding protein involved in single-strand DNA break

repair, double-strand DNA break repair and base excision repair. Resolves

abortive DNA ligation intermediates formed either at base excision sites,

or when DNA ligases attempt to repair non-ligatable breaks induced by

reactive oxygen species. Catalyzes the release of adenylate groups

covalently linked to 5'-phosphate termini, resulting in the production of 5'-

phosphate termini that can be efficiently rejoined. Also able to hydrolyze

adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine

tetraphosphate (AppppA), but with lower catalytic activity.
APTX Sequence databases
EMBL DDBJ GenBank
APTX 3D structure databases
ModBase
APTX Protein-protein interaction databases
STRING
APTX Proteomic databases
PRIDE
APTX Genome annotation databases
Ensembl GeneID KEGG UCSC
APTX Organism specific databases
CTD MGI
APTX Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
APTX Gene expression databases
Bgee ArrayExpress Genevestigator
APTX Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY