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| Rat cd163 (aa 39-365) |
| CD163 Swiss Prot | | D3Z9U2 |
| CD163 Protein names | | CD163 antigen (Predicted) (Uncharacterized protein) |
| CD163 Gene names | | Cd163 Cd163_predicted rCG_29882 |
| Organism | | Rat |
| CD163 Entry name | | D3Z9U2_RAT |
| CD163 Codon optimized cDNA Clone |
| CD163 cDNA Cat | | RPV0222 |
| cDNA Tag | | cDNA CD163 contains A 6x histidine tag |
| Condon optimized CD163 cDNA Formulation | | Liquid |
| Condon optimized CD163 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD163 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD163 Protein |
| Recombinant CD163 Protein Cat | | PV0222 |
| CD163 Protein Source | | Recombinant protein |
| Recombinant CD163 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD163 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD163 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD163 contains A 6x histidine tag |
| Recombinant CD163 Protein Formulation | | Liquid |
| Recombinant CD163 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD163 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD163 SUBUNIT | | - |
| CD163 Subcellular locations | | - |
| CD163 FUNCTION According to UniProtKB Swiss Prot | | Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and |
| | multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol |
| | triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.; After shedding, the soluble form (sCD163) may play an anti- |
| | inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions. |
| CD163 Sequence databases | | EMBL | DDBJ | GenBank |
| CD163 3D structure databases | | ModBase |
| CD163 Protein protein interaction databases | | STRING |
| CD163 Proteomic databases | | PRIDE |
| CD163 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD163 Organism specific databases | | CTD | MGI |
| CD163 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD163 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD163 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |