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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
  • Amine-terminated
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  • CDI-activated
  • DVS-activated
  • DADPA-terminated
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Reversed-Phase  Beads
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  • Cyanopropyl
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Ion Exchange Beads
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Antibody Purification & IP
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Antibody Immobilization
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Recombinant Protein
Purification
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Peptide Immobilization
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Abundant Protein Removal
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EDTA-Magnetic BEads
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Rat cd163 (aa 39-365)
CD163 Swiss Prot
D3Z9U2
CD163 Protein names
CD163 antigen (Predicted) (Uncharacterized protein)
CD163 Gene names
Cd163 Cd163_predicted rCG_29882
Organism
Rat
CD163 Entry name
D3Z9U2_RAT
CD163 Codon optimized cDNA Clone
CD163 cDNA Cat
RPV0222
cDNA Tag
cDNA CD163 contains A 6x histidine tag
Condon optimized CD163 cDNA Formulation
Liquid
Condon optimized CD163 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD163 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD163 Protein
Recombinant CD163 Protein Cat
PV0222
CD163 Protein Source
Recombinant protein
Recombinant CD163 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD163 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD163 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD163 contains A 6x histidine tag
Recombinant CD163 Protein Formulation
Liquid
Recombinant CD163 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD163 SUBUNIT
-
CD163 Subcellular locations
-
CD163 FUNCTION According to UniProtKB Swiss Prot
Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and

multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol

triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.; After shedding, the soluble form (sCD163) may play an anti-

inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.
CD163 Sequence databases
EMBL DDBJ GenBank
CD163 3D structure databases
ModBase
CD163 Protein protein interaction databases
STRING
CD163 Proteomic databases
PRIDE
CD163 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD163 Organism specific databases
CTD MGI
CD163 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD163 Gene expression databases
Bgee ArrayExpress Genevestigator
CD163 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY