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| Mouse CD172a (aa 29 – 360) |
| CD172a Swiss Prot | | P97797 |
| CD172a Protein names | | Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a) |
| CD172a Gene names | | Sirpa Bit Myd1 Ptpns1 Shps1 Sirp |
| Organism | | Mouse |
| CD172a Entry name | | SHPS1_MOUSE |
| CD172a Codon optimized cDNA Clone |
| CD172a cDNA Cat | | RPV0253 |
| cDNA Tag | | cDNA CD172a contains A 6x histidine tag |
| Condon optimized CD172a cDNA Formulation | | Liquid |
| Condon optimized CD172a cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD172a cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD172a Protein |
| Recombinant CD172a Protein Cat | | PV0253 |
| CD172a Protein Source | | Recombinant protein |
| Recombinant CD172a Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD172a Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD172a Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD172a contains A 6x histidine tag |
| Recombinant CD172a Protein Formulation | | Liquid |
| Recombinant CD172a Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD172a Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD172a SUBUNIT | | SUBUNIT: Binds PTPN11 when tyrosine-phosphorylated, except in macrophages, where it primarily binds PTPN6. Binds GRB2 vitro. Binds FGR. Binds JAK2 irrespective of its phosphorylation status and forms a stable complex. Binds SCAP1 and/or SCAP2. The resulting complex recruits FYB. Binds PTK2B (By similarity). |
| CD172a Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD172a FUNCTION According to UniProtKB Swiss Prot | | Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell |
| | adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature |
| | dendritic cells (By similarity). |
| CD172a Sequence databases | | EMBL | DDBJ | GenBank |
| CD172a 3D structure databases | | ModBase |
| CD172a Protein protein interaction databases | | STRING |
| CD172a Proteomic databases | | PRIDE |
| CD172a Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD172a Organism specific databases | | CTD | MGI |
| CD172a Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD172a Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD172a Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
