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Rat CD178 (aa 100 – 278 )
CD178 Swiss Prot
P36940
CD178 Protein names
Tumor necrosis factor ligand superfamily member 6 (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form]
CD178 Gene names
Faslg Apt1Lg1 Cd95l Fasl Tnfsf6
Organism
Rat
CD178 Entry name
TNFL6_RAT
CD178 Codon optimized cDNA Clone
CD178 cDNA Cat
RPV0261
cDNA Tag
cDNA CD178 contains A 6x histidine tag
Condon optimized CD178 cDNA Formulation
Liquid
Condon optimized CD178 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD178 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD178 Protein
Recombinant CD178 Protein Cat
PV0261
CD178 Protein Source
Recombinant protein
Recombinant CD178 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD178 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD178 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD178 contains A 6x histidine tag
Recombinant CD178 Protein Formulation
Liquid
Recombinant CD178 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD178 SUBUNIT
SUBUNIT: Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1 (By similarity).
CD178 Subcellular locations
SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein (By similarity). ; SUBCELLULAR LOCATION: Tumor necrosis factor ligand superfamily member 6, soluble form: Secreted (By similarity).
CD178 FUNCTION According to UniProtKB Swiss Prot
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects (By similarity).
CD178 Sequence databases
EMBL DDBJ GenBank
CD178 3D structure databases
ModBase
CD178 Protein protein interaction databases
STRING
CD178 Proteomic databases
PRIDE
CD178 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD178 Organism specific databases
CTD MGI
CD178 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD178 Gene expression databases
Bgee ArrayExpress Genevestigator
CD178 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY