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| Human cd18 (aa 23 – 423) |
| CD18 Swiss Prot | | P05107 |
| CD18 Protein names | | Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18) |
| CD18 Gene names | | ITGB2 CD18 MFI7 |
| Organism | | Human |
| CD18 Entry name | | ITB2_HUMAN |
| CD18 Codon optimized cDNA Clone |
| CD18 cDNA Cat | | RPV0267 |
| cDNA Tag | | cDNA CD18 contains A 6x histidine tag |
| Condon optimized CD18 cDNA Formulation | | Liquid |
| Condon optimized CD18 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD18 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD18 Protein |
| Recombinant CD18 Protein Cat | | PV0267 |
| CD18 Protein Source | | Recombinant protein |
| Recombinant CD18 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD18 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD18 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD18 contains A 6x histidine tag |
| Recombinant CD18 Protein Formulation | | Liquid |
| Recombinant CD18 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD18 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD18 SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-2 associates with either alpha-L, alpha-M, alpha-X or alpha-D. Interacts with COPS5 and RANBP9. |
| CD18 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD18 FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. |
| CD18 Sequence databases | | EMBL | DDBJ | GenBank |
| CD18 3D structure databases | | ModBase |
| CD18 Protein protein interaction databases | | STRING |
| CD18 Proteomic databases | | PRIDE |
| CD18 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD18 Organism specific databases | | CTD | MGI |
| CD18 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD18 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD18 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
