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| Human cd104 (aa 131 – 329) |
| CD104 Swiss Prot | | P16144 |
| CD104 Protein names | | Integrin beta-4 (GP150) (CD antigen CD104) |
| CD104 Gene names | | ITGB4 |
| Organism | | Human |
| CD104 Entry name | | ITB4_HUMAN |
| CD104 Codon optimized cDNA Clone |
| CD104 cDNA Cat | | RPV0027 |
| cDNA Tag | | cDNA CD104 contains A 6x histidine tag |
| Condon optimized CD104 cDNA Formulation | | Liquid |
| Condon optimized CD104 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD104 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD104 Protein |
| Recombinant CD104 Protein Cat | | PV0027 |
| CD104 Protein Source | | Recombinant protein |
| Recombinant CD104 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD104 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD104 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD104 contains A 6x histidine tag |
| Recombinant CD104 Protein Formulation | | Liquid |
| Recombinant CD104 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD104 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD104 SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-4 associates with alpha-6. Interacts (via cytoplasmic region) with COL17A1 (via cytoplasmic region). Interacts (via cytoplasmic region) with DST isoform 3 (via N-terminus). Isoform beta-4a interacts (via cytoplasmic domain) with DST (via N-terminus). Interacts with RAC1. |
| CD104 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. Cell junction, hemidesmosome. Note=Colocalizes with DST at the leading edge of migrating keratinocytes. |
| CD104 FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. |
| CD104 Sequence databases | | EMBL | DDBJ | GenBank |
| CD104 3D structure databases | | ModBase |
| CD104 Protein protein interaction databases | | STRING |
| CD104 Proteomic databases | | PRIDE |
| CD104 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD104 Organism specific databases | | CTD | MGI |
| CD104 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD104 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD104 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |