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| Human cd195 ( extracellular domain fused GFP at C-terminal) |
| CD195 Swiss Prot | | P51681 |
| CD195 Protein names | | C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195) |
| CD195 Gene names | | CCR5 CMKBR5 |
| Organism | | Human |
| CD195 Entry name | | CCR5_HUMAN |
| CD195 Codon optimized cDNA Clone |
| CD195 cDNA Cat | | RPV0301 |
| cDNA Tag | | cDNA CD195 contains A 6x histidine tag |
| Condon optimized CD195 cDNA Formulation | | Liquid |
| Condon optimized CD195 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD195 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD195 Protein |
| Recombinant CD195 Protein Cat | | PV0301 |
| CD195 Protein Source | | Recombinant protein |
| Recombinant CD195 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD195 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD195 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD195 contains A 6x histidine tag |
| Recombinant CD195 Protein Formulation | | Liquid |
| Recombinant CD195 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD195 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD195 SUBUNIT | | SUBUNIT: Interacts with PRAF2. Interacts with HIV-1 surface protein gp120. Efficient ligand binding to CCL3/MIP-1alpha and CCL4/MIP-1beta requires sulfation, O-glycosylation and sialic acid modifications. Glycosylation on Ser-6 is required for efficient binding of CCL4. Interacts with ADRBK1. Interacts with ARRB1 and ARRB2. |
| CD195 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. |
| CD195 FUNCTION According to UniProtKB Swiss Prot | | Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. |
| CD195 Sequence databases | | EMBL | DDBJ | GenBank |
| CD195 3D structure databases | | ModBase |
| CD195 Protein protein interaction databases | | STRING |
| CD195 Proteomic databases | | PRIDE |
| CD195 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD195 Organism specific databases | | CTD | MGI |
| CD195 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD195 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD195 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
