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Mouse Rhob (aa 1-196)
Rhob Swiss Prot#
P62746
Rhob Protein names
Rho-related GTP-binding protein RhoB
Rhob Gene names
Rhob (Arhb)
Organism
Mouse
Rhob Entry name
RHOB_MOUSE
Rhob Codon optimized cDNA Clone
Rhob CDNA Cat#
RPU0311
cDNA Tag
cDNA Rhob Contains A 6x histidine tag
Condon optimized Rhob CDNA Formulation
Liquid
Condon optimized Rhob CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized Rhob cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Rhob Protein
Recombinant Rhob Protein Cat#
PU0311
Rhob Protein Source
Recombinant protein.
Recombinant Rhob Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Rhob Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Rhob Protein Activity
N/A
Recombinant protein Tag
Recombinant Rhob contains A 6x histidine tag
Recombinant Rhob Protein Formulation
Liquid
Recombinant Rhob Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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Rhob Protein family
Small GTPase superfamily, Rho family
Rhob Subcellular locations
Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor.

Nucleus.
Rhob FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Mediates apoptosis in neoplastically transformed cells after

DNA damage. Not essential for development but affects cell adhesion and

growth factor signaling in transformed cells. Plays a negative role in

tumorigenesis as deletion causes tumor formation. Involved in intracellular

protein trafficking of a number of proteins. Targets PKN1 to endosomes and

is involved in trafficking of the EGF receptor from late endosomes to

lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT

which promotes endothelial cell survival during vascular development.
Rhob Sequence databases
EMBL DDBJ GenBank
Rhob 3D structure databases
ModBase
Rhob Protein-protein interaction databases
STRING
Rhob Proteomic databases
PRIDE
Rhob Genome annotation databases
Ensembl GeneID KEGG UCSC
Rhob Organism specific databases
CTD MGI
Rhob Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Rhob Gene expression databases
Bgee ArrayExpress Genevestigator
Rhob Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY