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Human CDC14B (aa 1-498)
CDC14B Swiss Prot#
O60729
CDC14B Protein names
Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16)

(CDC14 cell division cycle 14 homolog B)
CDC14B Gene names
CDC14B
Organism
Human
CDC14B Entry name
CC14B_HUMAN
CDC14B Codon optimized cDNA Clone
CDC14B CDNA Cat#
RPT0319
cDNA Tag
cDNA CDC14B Contains A 6x histidine tag
Condon optimized CDC14B CDNA Formulation
Liquid
Condon optimized CDC14B CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized CDC14B cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant CDC14B Protein
Recombinant CDC14B Protein Cat#
PT0319
CDC14B Protein Source
Recombinant protein.
Recombinant CDC14B Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CDC14B Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CDC14B Protein Activity
N/A
Recombinant protein Tag
Recombinant CDC14B contains A 6x histidine tag
Recombinant CDC14B Protein Formulation
Liquid
Recombinant CDC14B Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Place Order for Recombinant CDC14B Protein or cDNA
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CDC14B Protein family
Protein-tyrosine phosphatase family, Non-receptor class CDC14 subfamily
CDC14B Subcellular locations
Nucleus > nucleolus. Nucleus > nucleoplasm.
CDC14B FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Dual-specificity phosphatase involved in DNA damage

response. Essential regulator of the G2 DNA damage checkpoint: following

DNA damage, translocates to the nucleus and dephosphorylates

FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome

(APC/C). Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to

the ubiquitination of PLK1, preventing entry into mitosis. Preferentially

dephosphorylates proteins modified by proline-directed kinases.
CDC14B Sequence databases
EMBL DDBJ GenBank
CDC14B 3D structure databases
ModBase
CDC14B Protein-protein interaction databases
STRING
CDC14B Proteomic databases
PRIDE
CDC14B Genome annotation databases
Ensembl GeneID KEGG UCSC
CDC14B Organism specific databases
CTD MGI
CDC14B Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CDC14B Gene expression databases
Bgee ArrayExpress Genevestigator
CDC14B Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY