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Human DOC2A (aa 1-400)
DOC2A Swiss Prot#
Q14183
DOC2A Protein names
Double C2-like domain-containing protein alpha (Doc2-alpha) (Doc2)
DOC2A Gene names
DOC2A
Organism
Human
DOC2A Entry name
DOC2A_HUMAN
DOC2A Codon optimized cDNA Clone
DOC2A CDNA Cat#
RPU0036
cDNA Tag
cDNA DOC2A Contains A 6x histidine tag
Condon optimized DOC2A CDNA Formulation
Liquid
Condon optimized DOC2A CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized DOC2A cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant DOC2A Protein

Recombinant DOC2A Protein Cat#
PU0036
DOC2A Protein Source
Recombinant protein.
Recombinant DOC2A Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DOC2A Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DOC2A Protein Activity
N/A
Recombinant protein Tag
Recombinant DOC2A contains A 6x histidine tag
Recombinant DOC2A Protein Formulation
Liquid
Recombinant DOC2A Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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DOC2A Protein family
-
DOC2A Subcellular locations
Lysosome. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle

membrane; Peripheral membrane protein. Cell junction > synapse >

synaptosome.
DOC2A FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Calcium sensor which most probably regulates fusion of

vesicles with membranes. Binds calcium and phospholipids. May be

involved in calcium dependent neurotransmitter release through the

interaction with UNC13A. May be involved in calcium-dependent

spontaneous release of neurotransmitter in absence of action potentials in

neuronal cells. Regulates Ca(2+)-dependent secretory lysosome exocytosis

in mast cells.
DOC2A Sequence databases
EMBL DDBJ GenBank
DOC2A 3D structure databases
ModBase
DOC2A Protein-protein interaction databases
STRING
DOC2A Proteomic databases
PRIDE
DOC2A Genome annotation databases
Ensembl GeneID KEGG UCSC
DOC2A Organism specific databases
CTD MGI
DOC2A Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DOC2A Gene expression databases
Bgee ArrayExpress Genevestigator
DOC2A Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY