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Human PAK4 (aa 1- 591)
PAK4 Swiss Prot#
O96013
PAK4 Protein names
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21 kinase

4) (PAK-4)
PAK4 Gene names
PAK4 (KIAA1142)
Organism
Human
PAK4 Entry name
PAK4_HUMAN
PAK4 Codon optimized cDNA Clone
PAK4 CDNA Cat#
RPT0370
cDNA Tag
cDNA PAK4 Contains A 6x histidine tag
Condon optimized PAK4 CDNA Formulation
Liquid
Condon optimized PAK4 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PAK4 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PAK4 Protein
Recombinant PAK4 Protein Cat#
PT0370
PAK4 Protein Source
Recombinant protein.
Recombinant PAK4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PAK4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PAK4 Protein Activity
N/A
Recombinant protein Tag
Recombinant PAK4 contains A 6x histidine tag
Recombinant PAK4 Protein Formulation
Liquid
Recombinant PAK4 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PAK4 Protein family
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20

subfamily
PAK4 Subcellular locations
-
PAK4 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Activates the JNK pathway. Plays a role in the reorganization of

the actin cytoskeleton and in the formation of filopodia. Phosphorylates and

inactivates the protein phosphatase SSH1, leading to increased inhibitory

phosphorylation of the actin binding/depolymerizing factor cofilin.

Decreased cofilin activity may lead to stabilization of actin filaments.

Phosphorylates ARHGEF2.
PAK4 Sequence databases
EMBL DDBJ GenBank
PAK4 3D structure databases
ModBase
PAK4 Protein-protein interaction databases
STRING
PAK4 Proteomic databases
PRIDE
PAK4 Genome annotation databases
Ensembl GeneID KEGG UCSC
PAK4 Organism specific databases
CTD MGI
PAK4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PAK4 Gene expression databases
Bgee ArrayExpress Genevestigator
PAK4 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY