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Human PTPN6 (aa 1-595)
PTPN6 Swiss Prot#
P29350
PTPN6 Protein names
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Protein-

tyrosine phosphatase 1C) (PTP-1C) (Hematopoietic cell protein-tyrosine

phosphatase) (SH-PTP1) (Protein-tyrosine phosphatase SHP-1)
PTPN6 Gene names
PTPN6 (HCP) (PTP1C)
Organism
Human
PTPN6 Entry name
PTN6_HUMAN
PTPN6 Codon optimized cDNA Clone
PTPN6 CDNA Cat#
RPT0375
cDNA Tag
cDNA PTPN6 Contains A 6x histidine tag
Condon optimized PTPN6 CDNA Formulation
Liquid
Condon optimized PTPN6 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PTPN6 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PTPN6 Protein
Recombinant PTPN6 Protein Cat#
PT0375
PTPN6 Protein Source
Recombinant protein.
Recombinant PTPN6 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PTPN6 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PTPN6 Protein Activity
N/A
Recombinant protein Tag
Recombinant PTPN6 contains A 6x histidine tag
Recombinant PTPN6 Protein Formulation
Liquid
Recombinant PTPN6 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PTPN6 Protein family
Protein-tyrosine phosphatase family, Non-receptor class 2 subfamily
PTPN6 Subcellular locations
Cytoplasm. Nucleus.
PTPN6 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Plays a key role in hematopoiesis. This PTPase activity may

directly link growth factor receptors and other signaling proteins through

protein-tyrosine phosphorylation. The SH2 regions may interact with other

cellular components to modulate its own phosphatase activity against

interacting substrates. Together with MTUS1, induces UBE2V2 expression

upon angiotensin II stimulation.
PTPN6 Sequence databases
EMBL DDBJ GenBank
PTPN6 3D structure databases
ModBase
PTPN6 Protein-protein interaction databases
STRING
PTPN6 Proteomic databases
PRIDE
PTPN6 Genome annotation databases
Ensembl GeneID KEGG UCSC
PTPN6 Organism specific databases
CTD MGI
PTPN6 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PTPN6 Gene expression databases
Bgee ArrayExpress Genevestigator
PTPN6 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY