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| Human Cd247 (aa 22 – 164) |
| CD247 Swiss Prot | | P20963 |
| CD247 Protein names | | T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247) |
| CD247 Gene names | | CD247 CD3Z T3Z TCRZ |
| Organism | | Human |
| CD247 Entry name | | CD3Z_HUMAN |
| CD247 Codon optimized cDNA Clone |
| CD247 cDNA Cat | | RPV0415 |
| cDNA Tag | | cDNA CD247 contains A 6x histidine tag |
| Condon optimized CD247 cDNA Formulation | | Liquid |
| Condon optimized CD247 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD247 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD247 Protein |
| Recombinant CD247 Protein Cat | | PV0415 |
| CD247 Protein Source | | Recombinant protein |
| Recombinant CD247 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD247 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD247 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD247 contains A 6x histidine tag |
| Recombinant CD247 Protein Formulation | | Liquid |
| Recombinant CD247 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD247 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD247 SUBUNIT | | SUBUNIT: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. CD3-zeta forms either homodimers or heterodimers with CD3-eta. Interacts with SLA and SLA2. Interacts with DOCK2 and TRAT1. Interacts with HIV-1; this interaction up-regulates the expression of the Fas ligand (FASLG) at the cell surface. Interacts with |
| | HIV-2 Nef protein; this interaction induces down-regulation of cell surface TCR/CD3 complexes. Interacts with SHB. |
| CD247 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD247 FUNCTION According to UniProtKB Swiss Prot | | Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering. |
| CD247 Sequence databases | | EMBL | DDBJ | GenBank |
| CD247 3D structure databases | | ModBase |
| CD247 Protein protein interaction databases | | STRING |
| CD247 Proteomic databases | | PRIDE |
| CD247 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD247 Organism specific databases | | CTD | MGI |
| CD247 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD247 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD247 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
