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| Human CD261 (aa 24 – 239) |
| CD261 Swiss Prot | | O00220 |
| CD261 Protein names | | Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261) |
| CD261 Gene names | | TNFRSF10A APO2 DR4 TRAILR1 |
| Organism | | Human |
| CD261 Entry name | | TR10A_HUMAN |
| CD261 Codon optimized cDNA Clone |
| CD261 cDNA Cat | | RPV0430 |
| cDNA Tag | | cDNA CD261 contains A 6x histidine tag |
| Condon optimized CD261 cDNA Formulation | | Liquid |
| Condon optimized CD261 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD261 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD261 Protein |
| Recombinant CD261 Protein Cat | | PV0430 |
| CD261 Protein Source | | Recombinant protein |
| Recombinant CD261 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD261 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD261 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD261 contains A 6x histidine tag |
| Recombinant CD261 Protein Formulation | | Liquid |
| Recombinant CD261 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD261 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD261 SUBUNIT | | SUBUNIT: Can interact with TRADD and RIPK1. Interacts with ARAP1. |
| CD261 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD261 FUNCTION According to UniProtKB Swiss Prot | | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. |
| CD261 Sequence databases | | EMBL | DDBJ | GenBank |
| CD261 3D structure databases | | ModBase |
| CD261 Protein protein interaction databases | | STRING |
| CD261 Proteomic databases | | PRIDE |
| CD261 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD261 Organism specific databases | | CTD | MGI |
| CD261 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD261 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD261 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
